Don Tillman, professor of genetics, has never been on a second date. He is a man who can count all his friends on the fingers of one hand, whose lifelong difficulty with social rituals has convinced him that he is simply not wired for romance. So when an acquaintance informs him that he would make a 'wonderful' husband, his first reaction is shock.

Don and Rosie are about to face their most important project. Their son, Hudson, is having trouble at school: his teachers say he isn’t fitting in with the other kids, and they'd like Don and Rosie to think about getting an autism assessment. As his parents debate whether a diagnosis might help or hinder, Hudson has his own ideas. Meanwhile, Rosie is battling Judas at work, and Don is in hot water after the Genetics Lecture Outrage. The life-contentment...